Glossary of Terms​

Cells responsible for fat tissue formation.

Cells or tissue obtained from a donor.

A tissue graft from a donor of the same species as the recipient but not genetically identical.

Cells or tissues obtained from the same individual.

Cells responsible for cartilage formation.

Dimethyl Sulfoxide is used as cryoprotectant to help preserve organs, tissue and cell suspensions that are undergoing cryo preservation.

An industry guidance document for the regulation of human cells, tissue and cellular and tissue-based products (HCT/Ps).

An HCT/P that does not meet the criteria for 361 and therefore is regulated as a drug, device or biological product.

A list of criteria that allows a human cell and tissue products to be used without going through the investigational new drug protocols.

The repair, reconstruction, replacement or supplementation of a recipients cells or tissues with a human cell and tissue product (HCT/P) that performs the same basic function or functions in the recipient as in the donor.

Multipotent stromal cells that can differentiate into a variety of cell types; Osteoblasts, Chondrocytes, Myocytes, Neuronal cells and Adipocytes.

Processing that does not alter the relevant biological characteristics of cells or tissues.

Processing that does not alter the original relevant characteristics of the tissue relating to the tissue’s utility for reconstruction, repair, or replacement.

Multipotent cells can develop into more than one cell type but are more limited than pluripotent cells.

Cells responsible for muscle tissue formation.

Cells responsible for nerve cell formation.

Cells responsible for bone formation.

Pluripotent cells can give rise to all of the cell types that make up the body; embryonic stem cells are considered pluripotent.

A group of man-made medicines that contain the sulfonamide chemical group. It is not the same as sulfoxide used in DMSO.

Stem cells are biological cells that can differentiate into other types of cells and can divide to produce more of the same type of stem cells.

Totipotent cells can form all the cell types in a body, plus the extraembryonic, or placental, cells. Embryonic cells within the first couple of cell divisions after fertilization are the only cells that are totipotent.